Laila Marie Noëlle Padotzke was born on 24 December 2004 in Munzingen near Freiburg. Already at the age of six she had a small appearance in an episode of the crime series "Schmidt & Schmitt". In 2013 she played an orphan in the TV drama "Julia und der Offizier", who lives in the children's home of the title character Julia. In the same year she spoke and sang the leading role of Pepe in the radio play production "Pepe der kleine Wolf und Harry der Hase"; in 2018, at the age of just 13, she also illustrated the children's book that goes with it. In Lancelot von Naso's TV remake of Erich Kästner's "Das doppelte Lottchen" (2016) Padotzke played the small supporting role of Moni.    

Her first leading role was in Sven Unterwaldt's feature film "Vier zauberhafte Schwestern" (DE/AT/IT 2019), after the British children's and youth book series "Sprite Sisters". In it she embodied the sister Flame, who can master the element fire.